Week 5 of the NFL is opening with an all-California rivalry game on Thursday Night Football as the San Francisco 49ers head south to take on a fellow NFC West team, the Los Angeles Rams.
Both teams are coming into TNF with 3-1 records; the Niners were undefeated through Week 4 when they fell to the Jaguars; the Rams recorded their only loss in Week 3 to the Eagles. The 49ers are, so far, 2-0 in divisional play, while the Rams haven’t faced a divisional rival until tonight’s game.
Niners quarterback Brock Purdy will miss his third straight game this week with a toe injury, so Mac Jones will make his third start for the team. In two starts, Jones is 53-for-80 with 563 yards and 4 touchdowns.
- When: Sept. 25, 8:15 p.m. ET
- Where: SoFi Stadium (Inglewood, California)
- Streaming: Prime Video (try it free for 30 days)
Here’s how to Thursday Night Football live without cable, from anywhere in the USA.
Seahawks vs. Cardinals time:
Tonight’s (Sept. 25) Seahawks vs. Cardinals game is scheduled to begin at 8:15 p.m. ET.
“TNF Tonight” pregame coverage begins on Prime Video at 7 p.m. ET.
How to watch Seahawks vs. Cardinals for free:
Thursday Night Football is streaming exclusively on Amazon Prime subscriber to watch the series.
Once signed up, you can watch TNF online or using the Prime Video app on any Fire TV sticks.
Thursday Night Football schedule 2025:
- Week 5—Oct. 2: San Francisco 49ers at Los Angeles Rams
- Week 6—Oct. 9: Philadelphia Eagles at New York Giants
- Week 7—Oct. 16: Pittsburgh Steelers at Cincinnati Bengals
- Week 8—Oct. 23: Minnesota Vikings at Los Angeles Chargers
- Week 9—Oct. 30: Baltimore Ravens at Miami Dolphins
- Week 10—Nov. 6: Las Vegas Raiders at Denver Broncos
- Week 11—Nov. 13: New York Jets at New England Patriots
- Week 12—Nov. 20: Buffalo Bills at Houston Texans
- Week 13—Friday, Nov. 28 (Black Friday Game): Chicago Bears at Philadelphia Eagles
- Week 14—Dec. 4: Dallas Cowboys at Detroit Lions
- Week 15—Dec. 11: Atlanta Falcons at Tampa Bay Buccaneers
- Week 16—Dec. 18: Los Angeles Rams at Seattle Seahawks
- Week 17—Dec. 25: Denver Broncos at Kansas City Chiefs
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This article was written by cord-cutter-friendly deals, and information on how to watch your favorite sports teams, TV shows, and movies on every streaming service. Not only does Angela test and compare the streaming services she writes about to ensure readers are getting the best prices, but she’s also a superfan specializing in the intersection of shopping, tech, sports, and pop culture. Prior to joining Decider and The New York Post in 2023, she wrote about streaming and consumer tech at Insider Reviews