Brandon Aiyuk

Kyle Shanahan hopes to have San Francisco 49ers wide receiver Ricky Pearsall back in practice Wednesday.

On “49ers Talk,” co-hosts Jennifer Lee Chan and Matt Maiocco discuss San Francisco’s need for George Kittle to step up and be the Kittle of old.

San Francisco 49ers coach Kyle Shanahan provided an update on wide receiver Brandon Aiyuk’s recovery during the 2025 NFL season.

49ers coach Kyle Shanahan speaks with reporters before practice at the SAP Performance Facility on Wednesday in Santa Clara.

The San Francisco 49ers will not open wide receiver Brandon Aiyuk’s 21-day practice window ahead of their Week 9 game vs. the New York Giants.

The San Francisco 49ers have the largest sum of inactive salaries in the NFL heading into Week 9 of the 2025 season.

On “49ers Talk,” co-hosts Matt Maiocco and Jennifer Lee Chan detail how San Francisco’s injuries are impacting the team following its Week 8 loss.

49ers’ Kyle Shanahan, George Kittle and more speak to reporters following San Francisco’s 26-25 loss to the Houston Texans on Sunday at NRG Stadium.

Kyle Shanahan provided a positive update on San Francisco 49ers wide receiver Brandon Aiyuk’s return status.

49ers coach Kyle Shanahan speaks to reporters following San Francisco’s practice on Friday afternoon in Santa Clara.

49ers general manager John Lynch gave a promising update on Brandon Aiyuk’s progress as the All-Pro wideout recovers from a brutal knee injury.

49ers kicker Eddy Piñeiro spoke to Jennifer Lee Chan about his NFL journey and finding a home with San Francisco.

It doesn’t appear that Brandon Aiyuk is nearing a return to the field for the San Francisco 49ers.

Kyle Shanahan, Mac Jones, Christian McCaffrey and more speak to reporters after San Francisco’s 30-19 loss to the Tampa Bay Buccaneers on Sunday.

Kyle Shanahan shared that 49ers tight end George Kittle is a “long shot” to play in San Francisco’s Week 6 game against the Tampa Bay Buccaneers.

49ers coach Kyle Shanahan speaks with the media after San Francisco’s 26-23 overtime win vs. the Los Angeles Rams on Thursday at SoFi Stadium.

San Francisco GM John Lynch revealed that 49ers wide receiver Brandon Aiyuk is “not close” to a return this season.

49ers receiver Ricky Pearsall speaks to reporters before San Francisco’s practice on Wednesday in Santa Clara.

Fred Warner has “full confidence” in the San Francisco 49ers’ chances in Week 2 vs. the New Orleans Saints despite injuries.

San Francisco 49ers linebacker Fred Warner speaks to reporters before the team’s practice on Wednesday at Levi’s Stadium.