Your Mac includes accessibility tools that make Apple features available and easy to use by anyone. To access these tools, open System Settings, then click Accessibility in the sidebar. Accessibility settings are grouped into 4 categories:
Hearing: Use these features to show and customize captions on the screen, make and receive Real-Time Text (RTT) calls, get live captions of audio, and more.
Vision: Use these features to zoom in on the screen, make the pointer or menu bar bigger, apply color filters, and more.
Motor: Use these features to control your Mac and apps using spoken commands, keys on your keyboard, facial expressions, an onscreen keyboard, or assistive devices.
General: Customize your keyboard shortcuts to quickly turn accessibility features on or off.
Use VoiceOver, the built-in screen reader. VoiceOver describes aloud what appears on the screen and speaks the text in documents, webpages, and windows. Using VoiceOver, you control your Mac with the keyboard or trackpad gestures. You can also connect a refreshable braille display to your Mac to use with VoiceOver.
You can also use VoiceOver to:
Add alternative image descriptions that can be read by VoiceOver.
Add custom descriptions to your PDF signatures.
Store custom punctuation marks in iCloud.
Choose different international braille tables.
Use Siri for VoiceOver. If you prefer the natural voice of Siri, you can choose to use Siri for VoiceOver or Speech.
To turn on VoiceOver, do any of the following:
Press Command-F5. If VoiceOver is on already, pressing the keys turns it off.
Use Siri. Say something like: “Turn VoiceOver on” or “Turn VoiceOver off”.
If your Magic Keyboard has Touch ID, press and hold the Command key while you quickly press Touch ID three times.
Choose Apple menu > System Settings, then click Accessibility in the sidebar. Click VoiceOver on the right, then turn VoiceOver on or off.
To learn more about VoiceOver, including how to customize it to your needs, see the Get started with accessibility features on Mac
Comprehensive guide on Accessibility support in Apple Products